Browsing by Author "Fonnum, Frode"

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Behavioral changes following PCB 153 exposure in the Spontaneously Hypertensive rat - an animal model of Attention-Deficit/Hyperactivity disorder

Johansen, Espen Borgå; Fonnum, Frode; Lausund, Per; Walaas, S. Ivar; Bærland, Nora Elise; Wøien, Grete; Sagvolden, Terje (2014)

Background Attention-Deficit/Hyperactivity Disorder (ADHD) is a behavioral disorder affecting 3-5% of children. Although ADHD is highly heritable, environmental factors like exposure during early development to various ...
Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice

Sivertsen, T; Nygaard, AK; Mathisen, Gro Haarklou; Fonnum, Frode (2009)

4-Methylimidazole (4MeI) is a tremorogenic and convulsive agent of concern both in human and veterinary toxicology. The in vitro effects of 4MeI (5 μM–20 mM) on cerebral glutamate decarboxylase (GAD) activity and (in ...
Postnatal exposure to PCB 153 and PCB 180, but not to PCB 52, produces changes in measures of attention, activity level and impulsivity in outbred male Wistar Kyoto rats

Johansen, Espen Borgå; Knoff, Monica; Fonnum, Frode; Lausund, Per; Walaas, S. Ivar; Wøien, Grete; Sagvolden, Terje (2011)

Background Polychlorinated biphenyls (PCBs) are a class of organic compounds that bioaccumulate due to their chemical stability and lipophilic properties. Humans are prenatally exposed via trans-placental transfer, ...